Retinal Toxicity of Commercial Intravitreal Tissue Plasminogen Activator Solution in Cat Eyes
نویسندگان
چکیده
منابع مشابه
tissue plasminogen activator versus aspirin in central retinal vein occlusion
purpose: to compare the effect of tissue plasminogen activator (tpa) and aspirin in patients with central retinal vein occlusion. methods: a prospective interventional study was conducted on patients with central retinal vein occlusion of less than 28 days' duration. patients in the tpa group received 100 μg intravitreal tissue plasminogen activator and the patients who declined intravitre...
متن کاملTreatment of recent onset central retinal vein occlusion with intravitreal tissue plasminogen activator: a pilot study.
AIMS To study the effects of intravitreal tissue plasminogen activator (tPA) in recent onset central retinal vein occlusion (CRVO). METHODS 15 patients with recent onset CRVO (from 1-21 days' duration, mean 8 days) were given 75-100 microg of tPA intravitreally associate with low dose low molecular weight heparin. CRVO was perfused in nine patients and with mild ischaemia not exceeding 100 di...
متن کاملIntravitreal injection of tissue plasminogen activator for central retinal vein occlusion.
PURPOSE This pilot study evaluated the feasibility of intravitreal injections of tissue plasminogen activator (tPA) in eyes with central retinal vein occlusion (CRVO). METHODS Between August 1997 and October 2000, 9 eyes with CRVO were treated with intravitreal injection of tPA, 100 micrograms (50 micrograms/0.1 mL), and paracentesis. After the injection, each patient was placed at strict bed...
متن کاملIntravitreal Versus Subretinal Tissue Plasminogen Activator Injection for Submacular Hemorrhage.
BACKGROUND AND OBJECTIVE The objective of this study was to compare visual acuity outcomes between the following procedures used to treat submacular hemorrhages: pneumatic displacement followed by intravitreal tissue plasminogen activator (tPA) if needed (pneumatic ± tPA) and pars plana vitrectomy (PPV) with subretinal tPA (PPV + tPA). PATIENTS AND METHODS This is a retrospective chart review...
متن کاملEffect of Amiloride to Retinal Toxicity Induced by Tissue Plasminogen Activator
PURPOSE The effects of amiloride on cellular toxicity caused by tissue plasminogen activator (tPA) in mouse primary retinal cells were investigated. METHODS Primary retinal cell cultures were maintained using glial conditioned medium. Commercial tPA and L-arginine were added, and the level of cyclic guanosine monophosphate (cyclic-GMP) in the culture supernatant was assessed using an ELISA as...
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ژورنال
عنوان ژورنال: Archives of Ophthalmology
سال: 2000
ISSN: 0003-9950
DOI: 10.1001/archopht.118.5.659